Women in their 40s
Ten percent of all breast cancers hit women in their 40s, which is why doctors recommend annual or biannual screening mammograms for all women in this age range, regardless of risk factors.
Among the new risk factors that begin to come into play at this age are:
- The first full term pregnancy did not occur until after the age of 30
- Early beginning to menstruation
- Excessive consumption of alcohol
- Hormone therapy using estrogen to combat the symptoms of early-onset menopause
In each case, what is involved are behaviors or events that increase a woman’s lifelong exposure to estrogen, a female hormone connected to reproductivity that is used as a fuel source by the types of breast cancers commonly found in women over 40. Preventative measures against the effects of estrogen can include hormonal therapy to repress the functioning of the ovaries, or actual removal of the ovaries, either of which could be an option for women in high risk categories. Tamoxifen, a drug, which can attach itself to estrogen receptors and shut down cancer cell formation, is normally used for cancer treatment but is sometimes prescribed as a preventative measure for women in high risk categories. One bit of good news for all women over 40 is that the breast cancers that tend to develop from this age on are generally not as aggressive or deadly.
Women in their 50s and 60s
Between 80 and 85% of all women who are diagnosed with breast cancer do so during these two decades, so this is the time when precautionary actions become most important. Over 50% of those carrying genetic mutations in the BRCA 1 or 2 genes will eventually develop breast cancer, so any woman with this mutation who has not yet contracted the disease needs to be on high alert. Menopause occurring after the age of 55 is a new possible risk factor (longer exposure to estrogen again) and postmenopausal hormone therapy of course is most commonly administered to those in this age group. Obesity after menopause is yet another new risk factor, as fat cells release estrogen and become the body’s primary source for this hormone once the ovaries shut down. Because age is actually the number one risk factor for breast cancer, tamoxifen for the purposes of prevention is often prescribed for women over 60, regardless of whether or not any other risk factors are present.
The dialogue continues
What women need to know about breast cancer and their personal situations changes from decade to decade. The most important thing they need to know, however, is this: at least 90% of all breast cancers are curable if detected early. It is for this reason that the necessity of eternal vigilance is the ultimate message that women of every age need to absorb and remember.


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