Poll

What age where you diagnosed with breast cancer?

User login

Radical Lymph Node Surgery: Overused Treatment for Breast Cancer?

Share |
Radical lymph node surgery might be unnecessary for breast cancer

Most people associate breast cancer surgery with a mastectomy or lumpectomy. However, there is another kind of adjunct surgery that is commonly performed to help protect women against the ravages of metastatic breast cancer. This procedure entails the removal of multiple lymph nodes from underneath the arm on the side of body where the affected breast is located. Because breast cancer spreads first to the lymphatic system before moving on to other parts of the body, it has been believed that this procedure is necessary to stop breast cancer in its tracks, even if the lymph nodes selected for removal have no obvious signs of cancer at the time of the operation.

Lymph node surgery in the area of the armpit is a painful, invasive procedure that usually involves the cutting away of at least ten individual nodes. This surgery has been performed in combination with mastectomies and now lumpectomies for almost a century – it is literally an ancient strategy for helping women combat the deadly scourge of breast cancer.

But is this surgery actually necessary in every case? In recent years, questions about the overuse of this procedure have caused some oncologists to become more circumspect. Now, a study published in a recent edition of the Journal of the American Medical Association appears to validate the instincts of these wary medical professionals.

The Findings of the JAMA Report
This study, published in February 2011, was carried out over a five-year period, and involved some 900 women who had been diagnosed with a certain type of breast cancer that was normally treated in part with radical lymph node surgery. The cancers of these women had not yet spread to the lymph node system but the presence of cancer had been detected in one or two of the sentinel lymph nodes, which are the nodes located closest to the breast. Half the women in the study had radical lymph node surgery performed as a part of their overall treatment protocols, while the remaining women only had one or two sentinel nodes removed.

These surgeries took place at the John Wayne Cancer Institute in Santa Monica, California between 1999 and 2004, and the health of each woman who participated in the study was monitored carefully after their complete treatment programs had ended. What researchers discovered is that rates of survival were identical, as 92% of the women in each group were still alive after five years. The incidence of cancer recurrence was also all but equal, as 84% of the women in the sentinel node group and 82% of the women in the radical lymph node group were still cancer-free at the end of the five-year follow-up survey period.

These findings are highly significant, as sentinel node surgery is far less painful and does not have the same risk of serious side effects as the more extensive procedure. Radical lymph node surgery can lead to the onset of serious infection, as well as a condition called lymphedema. The latter is a painful, chronic swelling in the area of the arm and armpit that can range from mild to so severe that the mobility of the arm becomes seriously restricted.

Tempering the Excitement
The findings of the JAMA study are good news for many breast cancer sufferers. However, it needs to be emphasized that the results of this study are only applicable to about 20% of all breast cancers. In order for sentinel node surgery to be a viable alternative to the more radical operation, tumors in the breast can be no larger than a quarter, must have clean margins, and cannot have spread to other parts of the body, most especially the lymph node system as a whole.

It is also interesting to note that some doctors who have a history of performing radical lymph node surgery are expressing skepticism about the results of the new study, claiming the sample size is not large enough and the evidence is not conclusive. This judgment certainly seems counterintuitive and without merit. It is impossible not to wonder if this reaction may stem in part from defensiveness on the part of doctors who feel their past actions are being now being scrutinized with a critical eye.

Surgery-Happy Oncologists?
It was only ten years ago that the sentinel node biopsy came into use as a way to detect the possibility that breast cancer may have begun to spread into the lymph node system. Before that, removal of lymph nodes from beneath the arm was a way for oncologists to discover just how far breast cancer had actually spread. Given the technical limitations that existed until just a relatively short time ago, it is probably unfair to suggest that surgeons were performing clearly unnecessary surgeries on a regular basis for many decades.

However, once suspicions began to arise about the necessity for this surgery in some cases, medical professionals involved in the fight against breast cancer had a responsibility to sit up and take notice – and thankfully, some did. Those doctors who had already begun to partially phase radical lymph node surgery out of their surgical repertoire certainly deserve credit for doing the right thing, even before there was a definitive study that backed up what their sharply-honed insights and instincts were telling them.

Add new comment

Plain text

  • No HTML tags allowed.
  • Lines and paragraphs break automatically.