Preventative Mastectomies: Failures and Successes
Survival benefits were found for women under the age of 50 with estrogen-receptor breast cancer in stage I or II. Among this group, five-year survivor rates were 4.8% higher for women who had undergone a double mastectomy instead of only having their cancerous breast removed. This is not a great benefit by any means; nevertheless, it did represent the first scientific proof ever obtained that showed a survival advantage for those women who had chosen to have a preventative mastectomy.
Unfortunately, the number of women who fit this breast cancer profile is under 10%. For women whose cancers did not fit in this category - the vast majority - having a preventative mastectomy performed did not extend life span at all. While no one would dispute that this procedure can reduce the chances of breast cancer recurrence, in most cases cancers that recur are caught in the early stages, when they are more easily curable, because those who have had breast cancer in the past are always being closely monitored. With estrogen-receptor positive cancers (a clear majority among breast cancers diagnosed), hormone therapy with drugs like tamoxifen can disrupt the process through which cancer cells grow and divide by cutting off their supply of life-giving estrogen. In postmenopausal women, aromatase inhibitors used in targeted therapy can help stop the effects of estrogen released by the body's fat cells.
Facing Mortality
The desire of women to feel secure and safe inside their own bodies is understandable. However, the value of preventative mastectomies for women who have had breast cancer diagnosed and hope to keep it from coming back in the future once it is in remission has not been validated by the survival statistics. Having a healthy part of the body preemptively removed can help keep cancer from recurring in some cases. But what makes breast cancer so frightening to those who contract it is the fact that it brings them face to face with their own mortality. From the standpoint of survival, we now know that preventative mastectomies only provide tangible benefits to a small subset of breast cancer victims. For the rest, removing healthy breasts in the name of prevention appears to be a medical strategy without any real merit.


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